ABSTRACT
Plant derived biomolecules are said to possess various pharmacological actions. Curcumin obtained from rhizomes of Curcuma longa, is the primary bioactive molecule which exhibits antiviral, antinociceptive, anti-inflammatory, antipyretic and anti-fatigue effects. Recent studies reveal that curcumin also shows antiviral activity against many viruses such as dengue, hepatitis, zika, chikungunya, etc. Few research studies revealed that curcumin has binding potential to target a variety of SARSCov- 2 proteins. This chapter covers antiviral activity of curcumin with special focus on its role in inhibiting COVID-19 virus. These findings will be utilized to develop therapeutic lead using curcumin against COVID-19. © 2023 Nova Science Publishers, Inc.